GMAT Sentence Correction (SC) | Re: Carnivorous mammals can endure what would otherwise be

hi experts
appreciate if further explain the"having " in E, I am confused that when "having" is correct

I have some office problems which include "having" in options.

#51 OG 16
Neuroscientists, having amassed a wealth of knowledge over the past twenty years about the brain and its development from birth to adulthood, are now drawing solid conclusions about how the human brain grows and how babies acquire language.
(A) Neuroscientists, having amassed a wealth of knowledge
...

---