GMAT Sentence Correction (SC) | Re: Jerry knows it is futile to convince his wife to buy the

No, there is no difference in meaning - but be cautious about maintaining the parallel structure:

She is neither fond of X nor fond of Y.... correct

Neither is she fond of X nor is she fond of Y... correct.

Another alternative:
She is fond of neither X nor Y.... correct.

All the 3 structures convey the same meaning.
...

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