My 2 cents:
The defense lawyer and witnesses portrayed the accused as a victim of circumstance, his life uprooted by the media pressure to punish someone in the case.
(A) circumstance, his life
Correct - Uprooted here acts as an -ed modifier since his life is not the doer of the action. The phrase is a modifier.
(B) circumstance, and his life
Incorrect - with the introduction of 'and' - we expect to see two independent clauses; however, there is no main verb in the second clause.
(C) circumstance,
...
The defense lawyer and witnesses portrayed the accused as a victim of circumstance, his life uprooted by the media pressure to punish someone in the case.
(A) circumstance, his life
Correct - Uprooted here acts as an -ed modifier since his life is not the doer of the action. The phrase is a modifier.
(B) circumstance, and his life
Incorrect - with the introduction of 'and' - we expect to see two independent clauses; however, there is no main verb in the second clause.
(C) circumstance,
...
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