Codex Berinensis, a Florentine copy of an ancient roman medical treatise , is undated but contains clues to when it was produced. Its first eighty pages are by a single copyist, but the remaining twenty pages are by three different copyists, which indicates some significant disruption. Since a letter in handwriting identified as that of the fourth copyist mentions a plague that killed many people in florence in 1148, Codex Berinensis was probably produced in that year.
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