C is wrong for two reasons. First, we don't want to say "numbers." We can have a large number of people or a small number of people, but it's still just one number. Second, "number(s)" doesn't imply a large amount (it could be any number), so it doesn't fit with the idea of the sentence, which is that even large efforts/expenditures will not achieve what we want. We can fix both problems with C by saying "a large number of staff members."
D isn't saying that the individual
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D isn't saying that the individual
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