B C D are awkward
A. The wife of the poet Shelly wrote the world-famous and increasingly relevant Gothic horror tale, Frankenstein, in response to a challenge to create a ghost story.
E. In response to a challenge to create a ghost story, the wife of the poet Shelly wrote the world-famous and increasingly relevant Gothic horror tale, Frankenstein.
"In response to a challenge to create a ghost story" this beginning is relevant followed by "the wife" rather than in option
...
A. The wife of the poet Shelly wrote the world-famous and increasingly relevant Gothic horror tale, Frankenstein, in response to a challenge to create a ghost story.
E. In response to a challenge to create a ghost story, the wife of the poet Shelly wrote the world-famous and increasingly relevant Gothic horror tale, Frankenstein.
"In response to a challenge to create a ghost story" this beginning is relevant followed by "the wife" rather than in option
...